This is an exciting time for the biotechnology sector. It
is growing at an enormous rate - almost 17% per annum. And
no wonder: Big Pharma is suffering from poor R & D productivity
and is looking to smaller biotech companies to fill the gap.
There were 70 deals between Big Pharma and biotech companies
in 1993. Last year there were 500.
There are many large therapeutic areas with unmet medical
needs - cancer and autoimmune diseases to name but two. Biotech
companies are, by their very nature, risk-taking ventures
focussed on innovation and they are very active in these
and in most other therapeutic areas. The challenges to biotechnology
business, investors and operational management teams are
great.
Risk... Only 1 in 10 biotech
companies is profitable.
Drug development is a risky game with only 1 in 100 candidates
succeeding at the pre-clinical stage and only 1 in 10 candidates
succeeding at the clinical stage. The costs of bringing a
new drug to market are immense and many biotechs’ are
facing a looming cash crunch: 20% of European biotechs’,
for instance, have less than 12 months cash remaining at
their current burn rates.